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Torsional Wave Elastography to Assess the Mechanical Properties of the Cornea

Showing high potential for clinical diagnosis because of its rapid performance time.

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Description

Corneal mechanical changes are believed to occur before any visible structural alterations observed during routine clinical screening. It proposed developing torsional waves elastographu (TWE) adapted to the specificities of the cornea. By measuring the displacements in the propagation plane perpendicular to the axis of the emitter, the effect of guided waves in plate-like media was proven negligible. Ex vivo experiments were carried out on porcine corneal samples considering a group of control and one group of alkali burn treatment (NH4OH) that modified the mechanical properties, establishing a predictive capacity of damage and intraocular pressure (IOP), paving the way for future in vivo studies.

Current needs

Corneal mechanical changes are believed to occur before any visible structural alterations observed during routine clinical screening. It proposed developing torsional waves elastographu (TWE) adapted to the specificities of the cornea. By measuring the displacements in the propagation plane perpendicular to the axis of the emitter, the effect of guided waves in plate-like media was proven negligible. Ex vivo experiments were carried out on porcine corneal samples considering a group of control and one group of alkali burn treatment (NH4OH) that modified the mechanical properties, establishing a predictive capacity of damage and intraocular pressure (IOP), paving the way for future in vivo studies.

Meet the team

Guillermo Rus Callborg

Actuación del Campus de excelencia cofinanciadas por la Unión Europea a través del Fondo Europeo de Desarrollo Regional (FEDER) y la Consejería de Economía, Conocimiento, Empresas y Universidad, Junta de Andalucía.

Proyecto Singular ILIBERIS: Actuaciones Singulares de Transferencia de Conocimiento en el CEI BIOTIC.

Marco por el que se impulsa el desarrollo de Proyectos Singulares de actuaciones de transferencia en los Campus de Excelencia Internacional en las áreas de la Estrategia de Investigación e Innovación para la Especialización Inteligente de Andalucía (RIS3) con cargo al Programa Operativo FEDER 2014-2020 de Andalucía.