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Committed to change the fate of neurodegenerative diseases

Our goal is to stop the progression of serious neurodegenerative diseases with innovative therapeutic solutions


ONESTX is a biotechnology-based company, founded in 2020 as a spin-off of the Pablo Olavide University (Seville, Spain) and dedicated to the development of drugs to treat age-related neurodegenerative diseases.

ONESTX aims to bring a largely awaited solution to painful untreatable diseases related to neurodegeneration, gathering an enthusiastic group of talented researchers and biotechnological development experts.

The background of this start-up company was inspired by a research project carried out at the University Pablo de Olavide (UPO) in Seville (Spain). They discovered a new mechanism for increasing life span and improving memory in animal models, C. elegans and old mice, by increasing the level of certain neurosteroids. Furthermore, in models of neurodegenerative diseases (like Alzheimer’s disease) an improvement in cognitive disorders was observed.

Current needs

Investment, collaborators, Clinical Scientist Investment: Serie A: 8 million euros for the main clinical development programs, of which 4 millions euros for the clinical phase Ib/IIa , studies of the efficacy in Alzheimer Disease (2023-24).
Board: Collaborators with background in the pharmaceutical industry, in particular, with expertise in CNS drugs. International neuroscientists and clinical
neurologists from AD, PD and HD. Key opinion leaders in aging.
Team: chemist scientist, business development, clinical scientist, managers.

Meet the team


Project Manager

Actuación del Campus de excelencia cofinanciadas por la Unión Europea a través del Fondo Europeo de Desarrollo Regional (FEDER) y la Consejería de Economía, Conocimiento, Empresas y Universidad, Junta de Andalucía.

Proyecto Singular ILIBERIS: Actuaciones Singulares de Transferencia de Conocimiento en el CEI BIOTIC.

Marco por el que se impulsa el desarrollo de Proyectos Singulares de actuaciones de transferencia en los Campus de Excelencia Internacional en las áreas de la Estrategia de Investigación e Innovación para la Especialización Inteligente de Andalucía (RIS3) con cargo al Programa Operativo FEDER 2014-2020 de Andalucía.